Home | Contact Us

Registration is now open for the 2017-18 Worldwide Classroom® Connected Learning experiences.

Educators: Apply to Participate in our Adventures in Health Science and Medicine Program!
Enrollment is now open for this year’s Adventures in Health Science and Medicine (AHSM) program. Click here to learn more!

Dangerous Decibels® is a free, school-based program designed to teach 4th through 5th graders the concepts of noise-induced hearing loss prevention.

Connected Rounds is a grade-specific webinar series where students interact with Cleveland Clinic caregivers and complete hands-on activities as they delve deep into a designated health topic.

< Back to Search Results

Case-Control Association Analysis of Four SNPs With Atrial Fibrillation

Taejun Kim

View Poster View Presentation
School: Hudson High School
Internship Track: Translational Medicine
Year 2016
Mentor: Qing Wang, PhD
Department(s): Molecular Cardiology
Abstract: Genetic factors contribute significantly to the risk of Atrial Fibrillation (AF) . To date, there are 17 genetic loci identified for AF by genome-wide association study (GWAS). We conducted a GWAS for AF in Chinese population and identified 8 SNPs. In this project, we applied Taqman assay to examine associations of 4 SNPs with AF in the Cleveland Clinic AF cohort. One SNP rs2200733 was statistically significantly associated with AF (OR=1.85, P=1.16×10-9). The other 3 SNPs failed in replication. Larger sample are need to confirm such associations.